Free shipping on orders over $75 | 30-day money-back guarantee, even on opened bottles
Excellent
The Science
Every ingredient, every dose, and every combination in our formula is grounded in published clinical research. 4 ingredients. One capsule. The NAD+ stack longevity researchers actually recommend.
500mg
NAD+ per serving
Research-backed dose of direct NAD+
4
Synergistic ingredients
Each plays a specific role in supporting your NAD+ levels
8+
Referenced clinical studies
From Harvard, Washington University, Keio University, and multi-centre RCTs
500+
Enzymatic reactions
NAD+ powers over 500 processes in every cell of your body
The Decline
NAD+ is found in every cell of your body, powering over 500 reactions. It's essential for three things: fueling your cells' power plants, helping your body's DNA repair crew do its job, and turning on longevity genes. Without enough NAD+, your cells can't make energy, DNA damage piles up, and aging speeds up.
Research shows NAD+ levels drop roughly 50% by age 50. This happens because your body uses more NAD+ as inflammation increases, and produces less as its recycling system slows down. It becomes a vicious cycle — low NAD+ means less energy, slower recovery, and faster cellular aging.
Core Pathways
NAD+ isn't a one-trick molecule. It powers three systems your body depends on. When levels drop, all three suffer:
Cellular Energy (ATP Production)
NAD+ fuels your cells' power plants. Without it, your cells can't produce the energy your body runs on
DNA Repair (PARP Enzymes)
NAD+ powers your body's DNA repair crew. Without enough NAD+, damage piles up — one of the main drivers of aging
Longevity Genes (Sirtuins)
NAD+ turns on your longevity genes — a family of proteins that help manage inflammation, stress resistance, and cellular repair. They need NAD+ to work
science.zones.3.name
science.zones.3.description
science.zones.4.name
science.zones.4.description
The 4-Ingredient Synergy
Most NAD+ supplements have just one ingredient. Researchers don't take just one compound — they take a stack. NAD+ is the fuel, and Trans-Resveratrol is the ignition key that turns on your longevity genes. Together, research shows NAD+ levels increased up to 1.72x compared to NAD+ alone.
Vitamin B3 feeds your body's NAD+ recycling system, keeping levels topped up throughout the day. TMG is the ingredient most budget supplements skip — it replenishes what NAD+ metabolism uses up, keeping a key chemical process balanced. This is why researchers include TMG in their own stacks.
The Evidence
Our formula is built on real studies, not marketing. The Yoshino et al. trial (2021) found NAD+ supplementation improved metabolic health in postmenopausal women. Igarashi et al. (2022) showed it was safe, boosted NAD+ levels, and may support blood vessel health.
Yi et al. (2023) showed NAD+ significantly improved fitness and NAD+ levels in middle-aged adults. Liao et al. (2021) found improved exercise performance in runners. And the Sinclair Lab at Harvard showed that declining NAD+ disrupts how your cells communicate — something NAD+ supplementation may help reverse.
Ingredient Breakdown
Formulation Philosophy
We didn't stack trendy ingredients. We studied what longevity researchers actually take and why — then put the same 4 compounds in one capsule, each with a specific job.
500mg NAD+ for real cellular support, 250mg Trans-Resveratrol to activate longevity genes, 150mg Vitamin B3 to help your body recycle NAD+, and 100mg TMG to keep things balanced. No fillers, no hidden doses. Every ingredient and amount is right on the label.
NAD+ is the fuel for your longevity genes; resveratrol is the accelerator pedal. Having high NAD+ without turning on those genes is like having a full tank of gas with the engine off. The combination makes the difference.
David Sinclair, PhD
Harvard Medical School (paraphrased from published research)
Try our 4-ingredient NAD+ formula for 30 days. If you do not feel the difference, return it for a full refund — even if the bottle is open.
Shop NAD+Free shipping · 30-day guarantee · 4-ingredient formula